Stem Cell Therapy for Knee Arthritis in Arizona: What 15-Year Data Suggests

By Dr. Drew Timmermans, ND, RMSK Deep Dive Updated November 2, 2026
Illustrated side-view cross-section of a knee with osteoarthritis, showing worn articular cartilage and a narrowed joint space between the femur and tibia, with bone marrow edema in the tibial plateau beneath the damaged cartilage

Stem Cell Therapy for Knee Arthritis: What the 15-Year Evidence Suggests

Short Answer

  • Stem cell therapy for knee arthritis, using bone marrow concentrate drawn from your own pelvis, is a single non-surgical procedure studied as an alternative to knee replacement for people with knee osteoarthritis whose main problem is pain.
  • The longest published follow-up in regenerative medicine, a 15-year randomized study, suggests that when the concentrate is injected into the bone beneath the worn cartilage rather than only into the joint space, most treated knees had still not needed a replacement at the end of follow-up.
  • Most patients notice a response within the first 4 weeks, with the majority of improvement arriving over the first 6 months and healing continuing out to a year, though individual results may vary.

In short: a single image-guided bone marrow concentrate procedure, injected into the bone beneath the worn cartilage, is the stem cell approach with the longest follow-up behind it for avoiding a knee replacement.

If you live anywhere in Arizona and the only two options you keep hearing for a painful, worn-out knee are another cortisone shot or a total knee replacement, there is a third option, non-surgical stem cell therapy for knee arthritis, with longer follow-up data behind it than most people realize.

You may have already been through physical therapy that helped for a while, a cortisone injection or two that wore off faster each time, and an orthopedic visit that ended with "come back when you are ready for surgery," but the reason those treatments stopped working is usually that none of them addressed the bone beneath the cartilage, which is where much of the pain in an arthritic knee may be coming from. Once that structure is treated directly with non-surgical, image-guided stem cell therapy for knees, many patients start to improve within the first few weeks.

Stem cell therapy for knee arthritis at Regenerative Performance uses bone marrow concentrate, a stem cell therapy made from your own bone marrow, injected into the bone beneath the worn cartilage under x-ray (fluoroscopic) guidance and into the other painful structures around the joint under ultrasound guidance. Performed as a single procedure at our Gilbert, AZ clinic, it is used for adults with knee osteoarthritis who have been told they need a knee replacement but whose main limitation is pain rather than loss of function. The approach is built on 15-year randomized data comparing subchondral injection with joint-space injection. It does not work for every knee, and candidacy is decided only after a full diagnostic workup.

If you have knee arthritis that has not improved with physical therapy, chiropractic care, or cortisone, the next step is a detailed, in-person assessment to identify the exact tissues causing your pain and review non-surgical orthobiologic options like PRP and stem cell therapy.

Schedule a 2-hour evaluation for your knee arthritis at our Gilbert, AZ clinic (also serving Chandler, Mesa, Queen Creek, and the greater Phoenix area).

We limit how many new regenerative patients we accept each month to devote sufficient time and attention to each case.

Many of our knee arthritis patients travel from across Arizona and from out of state after being told a replacement was the only option left. Several have reported years of improvement after a single image-guided bone marrow concentrate procedure combined with strength-focused rehabilitation.

At our Gilbert clinic, we use image-guided stem cell therapy as a non-surgical treatment option for knee arthritis so patients from across Arizona can often delay or avoid a knee replacement.

Key Facts About Stem Cell Therapy for Knee Arthritis

Here is what you need to know about stem cell therapy for knee arthritis before deciding whether it is worth exploring.

  • What stem cell therapy is: Bone marrow aspirate concentrate (BMAC), a stem cell therapy made by drawing bone marrow from the back of your own pelvis and concentrating its stem cells and growth factors, then injecting that concentrate into the painful knee.
  • Who it helps: Adults with knee osteoarthritis whose pain originates from the arthritic joint and the bone beneath the worn cartilage, who have been told a knee replacement is the next step, and whose main limitation is pain rather than loss of motion or a deformed joint. Bone-on-bone imaging does not automatically rule you out.
  • How it works: The concentrate contains growth factors and signaling proteins that may support cartilage and bone repair. It is injected into the bone beneath the cartilage under x-ray (fluoroscopic) guidance and into the joint and surrounding soft tissue under ultrasound guidance.
  • Goal of treatment: To support healing in the structures generating your knee pain so you can delay or avoid a knee replacement.
  • Clinical outcomes: In our outcome registry, which tracks knees treated with PRP, bone marrow concentrate, or combination protocols, roughly 3 out of 4 patients (75%) treated for osteoarthritis report significant pain relief.
  • Timeline: Most patients notice a response within the first 4 weeks, the majority of improvement arrives over the first 6 months, and healing can continue out to 1 year. Individual results may vary.
  • Typical treatments: We start with one bone marrow concentrate procedure and track your individual response over the following year. In a small percentage of cases, a booster PRP injection is considered around 3 to 6 months based on how you responded.
  • Where: Regenerative Performance, Gilbert, AZ, serving Chandler, Mesa, Queen Creek, and patients from across Arizona.
  • Next step: Call 480-508-4226 to schedule a 2-hour evaluation for knee arthritis in Gilbert, AZ.

This article is especially useful if you have been told you are "bone on bone," your cortisone or gel injections have stopped working, and you want to understand the long-term evidence before agreeing to a knee replacement.

What Is Stem Cell Therapy for Knee Arthritis?

Stem cell therapy for knee arthritis is an autologous procedure, meaning it uses your own cells, in which bone marrow is drawn from the back of the pelvis, concentrated in the clinic the same day, and injected into the painful knee under image guidance. The concentrate, called bone marrow aspirate concentrate (BMAC) or bone marrow concentrate (BMC), contains stem cells along with growth factors and anti-inflammatory proteins.

At Regenerative Performance, stem cell therapy means one of two same-day forms of your own cells: bone marrow concentrate, or microfragmented adipose tissue (MFAT) taken from your own fat. For knee osteoarthritis, bone marrow concentrate is the form with the longest follow-up data. For select cases we also offer culture-expanded cells under the federal Right to Try Act, an investigational pathway processed in an FDA-compliant cGMP manufacturing facility.

Platelet-rich plasma (PRP) is different from stem cell therapy, because PRP concentrates the platelets and growth factors from your blood and delivers no stem cells, which is why we describe them as two separate options: PRP, and stem cell therapy (bone marrow concentrate and MFAT). Both are orthobiologic injections, and stem cell therapy appears to be the stronger of the two for a knee with advanced cartilage loss.

The same distinction applies to donor-derived products. Amniotic fluid, umbilical cord products, and exosomes are marketed as "stem cell treatments" by some clinics, but none of them are FDA approved for treating an arthritic knee, the FDA has warned about clinics marketing them this way, and a laboratory analysis of nine commercial amnion, chorion, umbilical cord, and amniotic fluid products identified no living cells in any of them (Becktell et al., Cartilage, 2020). Every stem cell procedure we perform uses only your own bone marrow or fat.

Why Does Where the Stem Cells Go Matter in an Arthritic Knee?

Where the stem cells go matters because the worn cartilage in an arthritic knee is not what hurts. Cartilage has no nerve endings, so as it thins, the load it used to cushion is transferred to the bone underneath, and that bone responds with tiny fractures, swelling inside the bone, and pain. Injecting the concentrate into that bone treats one of the main pain generators directly, and 15-year data suggests it postpones knee replacement far more often than a joint-space injection alone.

Split anterior illustration comparing a healthy knee joint on the left, with intact cartilage, normal joint space, and meniscus, to an osteoarthritic knee on the right, showing cartilage and bone wear, bone spurs (osteophytes), and subchondral bone damage

The Bone Beneath the Cartilage

The layer of bone just under the cartilage is called the subchondral bone. On an MRI of a painful arthritic knee, this bone often shows swelling (bone marrow edema), which is a marker of the microdamage happening under load. Most knee injections, whether cortisone, hyaluronic acid, PRP, or stem cells, are injected into the joint space and never reach this layer. An intraosseous injection, also called a subchondral injection, delivers bone marrow concentrate into the bone itself under x-ray (fluoroscopic) guidance.

Coronal MRI of a knee showing bone marrow edema in the tibia beneath the worn medial cartilage

Treating the Whole Joint, Not One Structure

Pain from an arthritic knee is usually coming from several places at once: the subchondral bone, the joint lining, the ligaments around the joint, the fat pad behind the kneecap, and small nerves that supply the joint. Instead of placing a single injection into the joint space and hoping it covers everything, the approach with the longest follow-up data injects bone marrow concentrate into the bone beneath the worn cartilage under x-ray guidance and treats the other painful structures around the joint under ultrasound guidance, each one confirmed on exam first. Treating only one structure while ignoring the others often explains why previous injections have failed.

Cell Dose

Placement is not the only variable that appears to matter, because a registry analysis of a specific bone marrow concentrate protocol for knee osteoarthritis, given together with platelet products, suggests that higher cell doses were associated with better pain scores at follow-up, a finding the authors called preliminary and in need of randomized confirmation (Centeno et al., BMC Musculoskelet Disord, 2015). How the marrow is collected and processed affects how many cells reach the knee, which is why collection technique and same-day processing matter more than a patient's age.

Important note: Bone marrow concentrate (BMC) is prepared from your own bone marrow during your visit. The device we use to prepare it is FDA-cleared; that clearance applies to the device, not to the treatment of knee osteoarthritis. There is no FDA-approved bone marrow product for knee osteoarthritis, and this use is considered investigational. The evidence is still developing. We offer BMC as one option for appropriately selected patients, not as a guaranteed or proven cure.

Published research tells you what happened in a trial population; it does not tell you what happens to the patients treated in a particular clinic. That is why we track every orthobiologic case in an outcome registry rather than estimating, and why the figures below are reported with their timepoints instead of as a single success rate.

Outcome Snapshot

These outcomes come from our patient outcome registry, powered by DataBiologics. The registry tracks knee and osteoarthritis cases treated with PRP, bone marrow concentrate, or combination protocols, so these figures describe orthobiologic treatment overall rather than stem cell therapy alone. Registry data updated July 2026.

  • In our registry, 49% of knee patients report significant pain relief at 1 month, 64% at 6 months, and 79% at 18 months.
  • Among patients treated for osteoarthritis across all body parts, 75% report significant pain relief, with an average pain reduction of 53%.

Those figures describe the whole orthobiologic knee and osteoarthritis cohort, not a promise about any one knee. Whether a subchondral bone marrow concentrate procedure is the right approach for yours depends on what the history, the hands-on exam, and your imaging show together.

Schedule a 2-hour evaluation for your knee arthritis at our Gilbert, AZ clinic.

What Does 15 Years of Data Suggest About Bone Marrow Concentrate and Knee Replacement?

Fifteen years of data from two randomized studies in France suggests that a single subchondral bone marrow concentrate injection allowed most treated knees to avoid a total knee replacement, and that injecting the concentrate into the bone rather than only into the joint space made the difference. These are the longest-running outcome studies in regenerative medicine, and they are the reason bone marrow concentrate, rather than PRP, is the more established option for this approach today.

In the first study, patients had osteoarthritis concentrated in the inner (medial) compartment of both knees. One knee received a single subchondral bone marrow concentrate injection, and the other received a total knee replacement during the same procedure. At a mean of 15 years, knee function scores were comparable between the two sides, and 82% of the bone marrow concentrate knees never needed a replacement. The 18% that did were replaced at a mean of ten years (Hernigou et al., Int Orthop, 2020). This suggests that the improvements seen with the subchondral injection were approximately equal to those of a total knee replacement for medial compartment osteoarthritis.

The second randomized trial indicates that among patients with osteoarthritis in both knees followed for an average of 15 years, 20% of the knees that received a subchondral bone marrow concentrate injection went on to total knee replacement, compared with 70% of the knees that received the same concentrate injected only into the joint space (Hernigou et al., Int Orthop, 2020). Same patients, same cells, different placement.

A 2016 systematic review of bone marrow aspirate concentrate for the knee suggests that all three included studies on knee osteoarthritis and all eight on focal cartilage defects reported good to excellent overall outcomes, while the authors noted that the evidence was limited by a small number of studies of varying quality and a lack of high-level randomized trials (Chahla et al., Orthop J Sports Med, 2016). Placebo-controlled data for bone marrow concentrate in knee osteoarthritis remains limited, and the 15-year studies compared the injection with surgery or with a different injection route, not with a sham.

Dr. Timmermans summarizes this French data in a short video, Bone Marrow Stem Cells for Knee Arthritis: What the Data Shows. In our own practice, patients treated with a subchondral bone marrow procedure several years ago, including some with end-stage arthritis who had been told they needed a replacement, continue to do well.

How Does Stem Cell Therapy for the Knee Compare to PRP?

Stem cell therapy and PRP have not been compared head to head at the subchondral level, so no study settles which is better for an arthritic knee. What exists is about one year of follow-up data on subchondral PRP and 15 years on subchondral bone marrow concentrate. That difference in track record, not a direct comparison, is why bone marrow concentrate is the more established choice when the bone beneath the cartilage is the target.

For pain relief, PRP and stem cell therapy can accomplish similar results in most situations, in our experience, but PRP usually requires more treatments to reach the effect and duration that stem cell therapy reaches sooner. Where the research suggests stem cell therapy may do a better job is in supporting repair of the structure itself, and swelling within the bone beneath the cartilage in knee osteoarthritis is one of the clearest examples. Even here, imaging and symptoms do not always move together: some patients feel worse while their imaging improves, and some feel better while it worsens, so we treat the structure seriously without promising a picture-perfect scan.

Cost is part of the conversation too, because some patients would do better with stem cell therapy but are not able to make this financial investment, and PRP therapy is then a great option, usually through more than one treatment. Cost never steers the diagnosis or the tissue-based recommendation, but it is a legitimate part of planning.

What Happens During a Stem Cell Procedure for Knee Arthritis?

A stem cell procedure for knee arthritis is a single visit, not a series of shots. Bone marrow is drawn from the back of the pelvis, concentrated the same day, and injected into the bone beneath the cartilage and the other painful structures around the knee, all under image guidance. The 15-year research behind this approach reflects one injection, not repeated ones.

Because the procedure includes a bone marrow harvest and an injection into bone, it is performed under twilight sedation with a dedicated anesthesia provider monitoring you throughout, along with long-acting nerve blocks. Most patients have increased soreness for 3 to 7 days afterward, and the discomfort after the nerve blocks wear off is usually managed with Tylenol alone. Procedures are performed sterile, and only your own marrow is used; we do not use donor cells from birth tissue.

Bone marrow concentrate syringes prepared on a sterile drape in a procedure room

Two features of recovery are worth knowing in advance, the first being that some patients feel a significant drop in pain in the first 7 to 14 days because the injected cells can release natural anti-inflammatory compounds, and that early relief wears off after a few weeks. Its fading does not mean the procedure failed. The treatment effect itself builds more slowly, with most patients noticing a response within the first 4 weeks and the majority of improvement arriving over the first 6 months.

Serious complications are uncommon when the procedure is performed sterile under image guidance. Because the concentrate is your own tissue, the risk of adverse reaction is extremely low, and there is no donor, so there is no donor-to-patient disease transmission. Among the cases with completed safety follow-up in our registry, zero severe treatment-related adverse events have been reported.

What to Expect at Our Gilbert, AZ Stem Cell Therapy Clinic

Regenerative Performance is located in Gilbert, AZ, and treats knee arthritis patients from across Arizona and out of state. The process follows the same four steps for every patient.

1

The 2-Hour Evaluation

Every new patient starts with a detailed 2-hour evaluation that includes a thorough history, a hands-on physical examination with specific tests for the knee joint, the ligaments and tendons around it, and the structures that refer pain into the knee, plus diagnostic ultrasound when indicated. Part of the exam is finding the movements and pressure points that reproduce your familiar pain, because that helps identify which structures are most likely contributing when we put it together with your history and, when needed, your imaging. We test the structures directly rather than relying solely on an x-ray or MRI.

The primary purpose of this evaluation is to identify the specific tissues causing your pain. This step is crucial because proper diagnosis is the single most important factor in regenerative treatment success.

2

Individualized Treatment Plan

Based on the evaluation, we determine whether you are a candidate for a subchondral bone marrow concentrate procedure or another regenerative approach. From there, we develop an orthobiologic plan specific to your case, including which structures will be treated, the sedation plan, the expected timeline, and your role in recovery.

We typically recommend supplements and peptides to support the healing process, because the first three months after a stem cell injection are the critical window where most healing occurs. Our goal is to give your body every advantage during that healing window.

3

Ultrasound- and X-Ray-Guided Stem Cell Injection

On your procedure day, bone marrow is drawn from the back of your pelvis under twilight sedation and processed in our clinic the same day to concentrate the cells and growth factors. Pre-procedure labs are a standard part of preparation for stem cell procedures, and transportation home is arranged in advance because sedation is used.

The concentrate is injected into the bone beneath the worn cartilage under x-ray (fluoroscopic) guidance, and into the joint, ligaments, and any other painful structures identified during your evaluation under ultrasound guidance. We treat each structure individually rather than relying on a single injection into the joint space.

4

Recovery and Follow-Up

After your procedure, we recommend resting for the remainder of that day so your body can begin the healing process. Expect soreness at the knee and at the pelvis where the marrow was drawn for the first several days, then a gradual return to daily activities over the following weeks, with high-impact activity held back until your response is clear. For most patients, we refer to a physical therapist who designs a strength-focused rehabilitation plan specific to your treatment and goals.

A brief early window of relief in the first one to two weeks is common and usually fades. The lasting response builds over the following months. Continued improvement through the first year is expected, not a sign that something is wrong.

We schedule follow-up assessments to track your progress using our outcome registry. That gives both you and our team objective data on how your treatment is working.

Schedule a 2-hour evaluation for your knee arthritis at our Gilbert, AZ clinic.

Who Is a Good Candidate for Stem Cell Therapy for Knee Arthritis in Arizona?

Stem cell therapy for knee arthritis is typically a good fit for adults with knee osteoarthritis who have been told they need a knee replacement, whose main limitation is pain rather than loss of function, and who want to avoid or delay surgery. Our 2-hour evaluation is designed to confirm this for your specific knee.

If you see yourself in the list below, subchondral bone marrow concentrate may be worth exploring.

  • Knee pain from osteoarthritis that limits what you do, with pain (not a locked or deformed joint) as the main problem
  • Told you are "bone on bone" or that a knee replacement is your only remaining option
  • Physical therapy, chiropractic care, or medications that did not produce lasting improvement
  • Cortisone or gel injections that helped temporarily and then wore off, or that you have chosen to avoid
  • Looking for a single, well-supported procedure rather than a series of ongoing injections
  • Want treatment aimed at the bone beneath the cartilage and the other structures generating your pain, not just the joint space
  • You are willing to invest in your health, as these are cash-pay procedures

Our clinic is in Gilbert, AZ. Patients travel in from across Arizona, from out of state, and internationally, and we schedule the evaluation and the procedure in a single trip for traveling patients. A history of cancer is reviewed case by case rather than ruled in or out automatically. During your evaluation, we will assess whether subchondral bone marrow concentrate is the right approach for your specific knee, or whether a different regenerative treatment such as PRP might be more appropriate.

If you are unsure whether orthobiologic injections like PRP or stem cell therapy are appropriate, or you are traveling from outside the Phoenix area, you can also call and ask about a brief 15 minute discovery call.

Frequently Asked Questions About Stem Cell Therapy for Knee Arthritis

Can stem cell therapy help me avoid a knee replacement?

Stem cell therapy using bone marrow concentrate can help some patients with knee osteoarthritis delay or avoid a knee replacement, and the longest follow-up data comes from 15-year randomized studies in which most knees treated with a subchondral injection had not gone on to replacement (Hernigou et al., 2020, Int Orthop). The deciding factors are where the concentrate is injected, how advanced the joint damage is, and whether pain rather than loss of function is the main limitation. It does not work for every knee, and surgery remains the right call for some patients.

Is stem cell therapy for the knee FDA approved?

Stem cell therapy for the knee using your own bone marrow concentrate is not FDA approved, because the FDA regulates products and devices rather than medical procedures and there is no FDA-approved bone marrow product for knee osteoarthritis. The equipment used to prepare the concentrate is FDA-cleared, but using your own concentrated marrow for this purpose remains under investigation. Culture-expanded stem cells are a separate investigational pathway offered under the federal Right to Try Act and are also not FDA approved.

What is the difference between stem cell therapy and PRP for the knee?

Stem cell therapy for the knee uses bone marrow concentrate or microfragmented fat containing your own stem cells, while PRP concentrates the platelets and growth factors from your blood and contains no stem cells. Bone marrow concentrate appears to be the stronger of the two for a knee with advanced cartilage loss and has 15 years of published follow-up for subchondral injection (Hernigou et al., 2020, Int Orthop), compared with about one year for subchondral PRP. PRP usually requires more treatments to reach a similar level of pain relief.

Does the placement of stem cells in the knee affect results?

Placement of the stem cells in the knee appears to matter a great deal. A randomized trial indicates that among patients with osteoarthritis in both knees followed for an average of 15 years, 20% of knees that received bone marrow concentrate injected into the bone beneath the cartilage went on to knee replacement, compared with 70% of knees that received the same concentrate injected only into the joint space (Hernigou et al., 2020, Int Orthop). The bone beneath the cartilage is one of the main pain generators in an arthritic knee, and a joint-space injection does not reach it.

What are the risks of stem cell therapy for the knee?

The risks of stem cell therapy for the knee using your own bone marrow are mainly temporary soreness and swelling at the knee and at the pelvis where the marrow was drawn, along with the uncommon risks of any injection, including bleeding, infection, or injury to nearby structures. Because the concentrate is your own tissue, the risk of adverse reaction is extremely low, and there is no donor, so there is no donor-to-patient disease transmission. Sedation carries its own small risks, which are reviewed with the anesthesia provider beforehand.

How successful is stem cell therapy for knee arthritis?

Published research on stem cell therapy for knee arthritis suggests good to excellent outcomes in most included studies and, in the longest follow-up, most knees treated with a subchondral bone marrow concentrate injection avoided replacement over 15 years (Chahla et al., 2016, Orthop J Sports Med; Hernigou et al., 2020, Int Orthop). Success depends on accurate diagnosis, placement, cell dose, and how advanced the arthritis is, and placebo-controlled evidence remains limited.

Am I a candidate for stem cell therapy if my knee is bone on bone?

A bone-on-bone knee does not automatically rule out stem cell therapy. Candidacy depends more on whether pain, rather than loss of function or a deformed joint, is the main limitation, and it cannot be fully determined until after a complete diagnostic workup. Patients with advanced arthritis whose goal is to avoid surgery are often reasonable candidates for a subchondral bone marrow concentrate procedure.

Is stem cell therapy covered by insurance in Arizona?

Stem cell therapy using bone marrow concentrate is typically not covered by insurance, in part because there is no FDA-approved bone marrow product for knee osteoarthritis and its use for this purpose remains under investigation. It is a cash-pay procedure at virtually every clinic that offers it. Cost depends on the number and complexity of structures treated. A fee range is available by phone, and a specific quote follows once the diagnosis is finalized at an in-person evaluation. HSA and FSA funds can often be applied.

Still have questions? The best way to get answers is a conversation. Call 480-508-4226.

About Dr. Timmermans

Dr. Drew Timmermans, ND, RMSK

Dr. Drew Timmermans, ND, RMSK

Dr. Drew Timmermans, ND, RMSK, is a naturopathic physician and registered musculoskeletal sonographer (RMSK) practicing at Regenerative Performance in Gilbert, AZ. He specializes in orthobiologic injections, including PRP, stem cell therapy, prolotherapy, and nerve hydrodissection, using ultrasound and fluoroscopic guidance to treat the specific structures causing chronic pain rather than suppressing symptoms.

Patients from across Arizona and out of state see him for chronic joint pain that has not responded to physical therapy, cortisone, or standard orthopedic care. He tracks patient outcomes in an orthobiologic outcome registry to refine diagnosis and treatment.

References
  1. Hernigou P, Delambre J, Quiennec S, Poignard A. Human bone marrow mesenchymal stem cell injection in subchondral lesions of knee osteoarthritis: a prospective randomized study versus contralateral arthroplasty at a mean fifteen year follow-up. International Orthopaedics. 2020;45(2):365-373. DOI: 10.1007/s00264-020-04571-4.
  2. Hernigou P, Bouthors C, Bastard C, Flouzat Lachaniette CH, Rouard H, Dubory A. Subchondral bone or intra-articular injection of bone marrow concentrate mesenchymal stem cells in bilateral knee osteoarthritis: what better postpone knee arthroplasty at fifteen years? A randomized study. International Orthopaedics. 2020;45(2):391-399. DOI: 10.1007/s00264-020-04687-7.
  3. Centeno C, Al-Sayegh H, Bashir J, Goodyear S, Freeman MD. A dose response analysis of a specific bone marrow concentrate treatment protocol for knee osteoarthritis. BMC Musculoskeletal Disorders. 2015;16(1). DOI: 10.1186/s12891-015-0714-z.
  4. Chahla J, Dean CS, Moatshe G, Pascual-Garrido C, Serra Cruz R, LaPrade RF. Concentrated Bone Marrow Aspirate for the Treatment of Chondral Injuries and Osteoarthritis of the Knee: A Systematic Review of Outcomes. Orthopaedic Journal of Sports Medicine. 2016;4(1). DOI: 10.1177/2325967115625481.
  5. Becktell L, Matuska AM, Hon S, Delco ML, Cole BJ, Begum L, Zhang S, Fortier LA. Proteomic Analysis and Cell Viability of Nine Amnion, Chorion, Umbilical Cord, and Amniotic Fluid-Derived Products. Cartilage. 2020;13(2_suppl):495S-507S. DOI: 10.1177/1947603520976767.

NOTE: This article provides general information to help the reader better understand regenerative medicine, nerve and musculoskeletal conditions, naturopathic approaches to pain, and related subjects. All content provided in this article, website, or any linked materials, including text, graphics, images, research, and outcomes, are not intended, and should not be used, as a substitute for direct medical advice, diagnosis, or treatment. Please always consult with a professional and licensed healthcare provider to discuss if any treatment is right for you.

Registry data from our single practice, powered by DataBiologics, is not a randomized clinical trial. Individual results may vary.

We limit how many new regenerative patients we accept each month to devote sufficient time and attention to each case. If you have been told a knee replacement is your only option left, the answer may be a precise diagnosis and a single image-guided bone marrow concentrate procedure, right here in Gilbert, AZ.

Schedule a 2-hour evaluation for your knee arthritis at our Gilbert, AZ clinic (also serving Chandler, Mesa, Queen Creek, and the greater Phoenix area).

If you are unsure whether orthobiologic injections like PRP or stem cell therapy are appropriate, or you are traveling from outside the Phoenix area, you can also call 480-508-4226 and ask about a brief 15 minute discovery call.

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