Perineural Injection Therapy
Perineural Injection Therapy (PIT) is an injection into the layer between your skin and your muscles, which is where many of the peripheral cutaneous nerves reside. These injections, which usually consist of buffered 5% dextrose, are directed toward treating neurogenic inflammation, which can be a cause of both acute and chronic pain. Neurogenic inflammation can arise as a result of direct nerve trauma, chronic arthritis, overuse injuries, sports injuries, and scar tissue. As there is no downtime from these injections, patients can receive treatment and can continue to exercise and be active the same day.
How Perineural
Injections Work
When cutaneous nerves pierce through both deep and superficial fascial layers to reach the skin, there is a high potential for entrapment. If entrapment occurs, inflammatory neuropeptides are released, which can cause inflammation and neuropathic pain. Friction injuries can also arise where cutaneous nerves cross over areas of bone, such as the kneecap, which also results in neurogenic inflammation and neuropathic pain. Neurogenic inflammation differs from other forms of inflammation in that it does not respond as well to cortisone injections or other anti-inflammatory drugs such as NSAID’s. Patients are commonly prescribed Lyrica or other neuropathic pain medications, which may or may not be useful.
When the perineural injection solution is injected in an area where cutaneous nerves are trapped, the pressure from the fluid can reduce some of that tension, resulting in a reduction in inflammation. In addition to this, the 5% dextrose appears to have a local physiological effect on the nerve, which can further reduce inflammation and the perception of pain. Lastly, as neurogenic inflammation can arise due to low levels of glucose surrounding the nerve (known as glucopenia), injecting dextrose to surround the affected nerves can provide the nerve with the dextrose it needs to function correctly.
Frequently Asked Questions
What are the risks and side effects?
Before any procedure with us, your physician will explain all potential risks and side effects in person.
Am I guaranteed results?
Like all medical procedures, PIT procedures have a success and failure rate. An initial consultation with a Physician will determine if you are a good candidate.
How many treatments will I need?
While each person and condition are different, the average number of treatments required for most patients is six to eight. These injections are usually performed every 1-3 weeks.
How soon can I return to activity?
One of the significant benefits of perineural injection therapy is that there is no downtime, and you can return to activity immediately after the injections.
What is the cost?
Because each patient is unique, both in their condition to be treated and in which approach is best for them, the pricing of procedures can vary considerably from patient to patient. An evaluation will give you a better idea of condition, treatment, and costs specific to your situation.
Does insurance cover this procedure?
Insurance does not cover this procedure, nor is Regenerative Performance contracted with any insurance companies.
How do I get started?
You can get started by booking an appointment with Dr. Timmermans by calling 480-508-4226
What to EXPECT:
Our approach
Here’s what you can expect when you work with us.
Detailed history and current health status
Your initial appointment will include a deep dive into your health history, as well as your current health status and what brought you in today.
Medical, lifestyle, and
behavioral evaluation
We will perform a medical evaluation and assess your current lifestyle, in addition to any behavioral or mental blocks that might be holding you back.
Treatment Plan
Using proven treatment modalities, health practices, lifestyle changes, supplementation, and regenerative medicine, we’ll create a plan that is tailored to your specific needs, getting you on the path to feeling your best.
